General Cell Lines and Cell Cultures
ATCC Myceliophthora thermophila
An ampoule containing viable cells (may include spores and mycelia) suspended in cryoprotectant.
ATCC Respiratory Exclusivity Panel
This panel of seven quantitative genomic and synthetic nucleic acid preparations was selected from respiratory pathogen strains commonly cited in exclusivity or cross-reactivity studies in SARS-CoV-2 EUA submissions and/or FDA 510(k) submissions.
Biochain Institute Inc Matched Pair - DNA - Human Primary and Metastatic Tumor Tissue: Kidney, 2x10 ug/PK
BioChain's human DNA matched pair products include: Primary Pair (PP), Primary and Metastasis Pair (PM). PP consists of DNA prepared from primary tumor and its adjacent normal tissue; PM consists of DNA prepared from primary tumor and corresponding ponding metastatic tumor. Genomic DNA in each pair is prepared from the same donor. This product line is designed foridentifying tumor-specific genes and tumor metastatic genes.
Medchemexpress LLC CD47 protein, rat (HEK293, His) | >95.0% | 10 UG
Recombinant rat CD47 extracellular domain expressed in HEK293 cells with a C-terminal His tag. Supplied lyophilized and intended for research use; the protein is highly pure and shows heterogeneous migration by SDS-PAGE due to glycosylation.
- Recombinant extracellular domain (Q19-K140) with C-terminal His tag.
- High purity (>95%) as determined by reducing SDS-PAGE.
- Apparent molecular weight 23-40 kDa because of glycosylation.
- Lyophilized formulation from 0.22 μm filtered PBS, pH 7.4.
- Recommended reconstitution at ≥100 μg/mL in ddH2O; aliquot and store at -20°C or -80°C for long term.
- Suitable for immunoassays, binding studies, and antibody characterization.
Eurofins Discoverx Ready-to-Assay κ Opioid Receptor Frozen Cells, 2 Vials of Cells. (HTS095RTA)
The Ready-to-Assay κ Opioid Receptor Frozen Cells are a simple, thaw-and-assay cell format for use in studying drug candidates (small molecules or biologics) targeting GPCRs. This assay assesses ligand (e.g. DADLE, DPDPE) based activation of OPRK1 GPCR activity via detection of increasing levels of intracellular calcium. The included cell line overexpresses OPRK1 alongside endogenous high levels of a promiscuous G-protein, coupling the receptor to the calcium signaling pathway. Upon activation of OPRK1, the resulting calcium activity can be fluorescently assayed. Ready-to-assay kits consist of two vials of the stably modified clonal cell line in a convenient thaw-and-use format. For detailed product information, User manual and datasheet, visit www.discoverx.com/products-applications/frozen-cells.
Genscript Corporation HEK293/TP Stable Cell Line
The thromboxane A2 (TxA2) receptor (TP) is a member of the G protein-coupled receptor (GPCR) superfamily which mediates TxA2-induced platelet aggregation and vasoconstriction Dysregulation of TxA2 synthesis and function has been implicated in the pathogenesis of a number of disease states including myocardial ischemia asthma pregnancy-induced hypertension and a variety of kidney diseases TP receptors (Thromboxane A2 receptors) are widely distributed among different organ systems and localized on both cell membranes and in intracellular structures Two isoforms of human TPs have been cloned from placenta (TP ) and endothelium (TP ) that differ in their mechanisms and kinetics of desensitization and internalization The TPs are linked via the Gq/G11 class of G proteins to phospholipase C (PLC) which hydrolyzes phosphoinositides to two potent second messengers inositol 1 4 5-trisphosphate which leads to an increase in cytoplasmic free calcium and diacylglycerol (DAG) which a
Eurofins Discoverx PathHunter CHO-K1 PTHR1 β-Arrestin Cell Line, 2 vials. (93-0315C2)
The PathHunter PTHR1 cell line is a stable, engineered cell line for use in studying drug candidates (small molecules or biologics) targeting GPCRs. This cell line enables assessment of ligand (e.g. PTH) based activation of PTHR1 GPCR activity via detection of β-arrestin recruitment. The included cell line overexpresses ProLink-tagged PTHR1 and EA-tagged β-Arrestin-2. Activation of PTHR1 stimulates the recruitment of β-Arrestin-2 and produces EFC signal. This stable modified cell line is provided as two vials of cryopreserved cells. For detailed product information, User Manual and datasheet, visit www.discoverx.com/gpcr.
Eurofins Discoverx PathHunter U2OS GHR-JAK1 Functional Assay, 2 vials. (93-0756C3)
The PathHunter GHR-JAK1 Functional assay cell line is a stable, engineered cell line for use in studying drug candidates (small molecules or biologics) targeting CTKs. This cell line enables assessment of GHR activation via detection of JAK1 mediated phosphorylation-induced SH2 domain protein recruitment. This product uses EFC technology. The included cell line overexpresses ProLink-tagged GHR cytokine receptor, an untagged CTK JAK1 and EA-tagged SH2 domain protein. Upon activation of the cytokine receptor, CTK-based receptor phosphorylation leads to SH2-EA recruitment and production of EFC signal. This stable modified cell line is provided as two vials of cryopreserved cells. For detailed product information, User Manual and datasheet, visit www.discoverx.com/kinases.
Eurofins Discoverx ChemiScreen APJ Apelin Receptor Stable Cell Line, 2 vials. (HTS068C)
The ChemiScreen APJ Apelin Receptor Stable Cell Line is an engineered cell line for use in studying drug candidates (small molecules or biologics) targeting GPCRs. This cell line enables assessment of ligand (e.g. apelin) based activation of AGTRL1 GPCR activity via detection of increasing levels of intracellular calcium. The included cell line overexpresses AGTRL1 alongside endogenous high levels of the promiscuous G protein, Gα15, coupling the receptor to the calcium signaling pathway. Upon activation of AGTRL1, the resulting calcium activity can be fluorescently assayed. This stable modified cell line is provided as two vials of cryopreserved cells. For detailed product information, visit www.discoverx.com/targets/gpcr-target-biology.
ATCC Pfizer Pneumococcal; polysaccharide powder; Type 24 (24F) 10mg
Purified pneumococcal polysaccharide type 24F is manufactured by Pfizer, Inc. for small quantity distribution by ATCC. The pneumococcal polysaccharide type 24F can be used to assay for type-specific antibodies, research immune responses, and study immunodeficiencies.
Eurofins Discoverx PathHunter Rat DRD2S β-Arrestin Cell-Based Assay Kit (CHO-K1)
The PathHunter Rat DRD2S β-Arrestin Stable Cell Line Assay (CHO-K1) contains a stable clonal cell line used to measure DRD2S (GPCR) activity via recruitment of β-Arrestin2. This is a complete kit that includes the cell vials and all required reagents needed for cell culture and running the assay.
Amsbio LLC eLuCidate™ HEK 293, TLR3/ISRE Reporter Cell Line
eLuCidate™ HEK 293 TLR3/ISRE Reporter Cell Line
ATCC Haemophilus influenzae; Strain KW20; genomic DNA
Genomic DNA is isolated from Haemophilus influenzae strain Rd (ATCC 51907). This whole-genome sequenced product can be used in PCR and other molecular biology applications.
Biochain Institute Inc Paraffin Tissue Section - Alzheimers Disease: Brain: Temporal Lobe, 5 slides/PK
BioChain's tissue products are based on the sample repository network established following the IRB-approved ethical standard and procedures. BioChain's formalin fixed paraffin embedded (FFPE) tissue section line encompasses a large selection of tissue sections which are suitable for immunohistochemistry and in situ hybridization assays. The tissue sections are approximately 5 um thick. Each slide contains tissue from single human diseased sample. Documentation of tissues' clinical histories may be available upon request. For those customers who want to perform FFPE DNA and RNA isolation, BioChain can provide tissue section slices in tubes instead of mounting them on glass slides.